Welcome to the Science behind our ingredients. At Rooted Owl™, we believe in transparency and making informed choices when it comes to the formulation of our products. We understand that you want to know exactly why we've chosen particular ingredients, so in this section, we provide you with a curated list of scientific studies that support our decisions.
Explore these resources to learn more about the rigorous research and testing that goes into our products, ensuring that you can trust our commitment to quality and efficacy.
For Anxiety and CBD and CBG:
1) A single dose of cannabidiol (CBD) positively influences measures of stress in dogs during separation and car travel - PMC.
2) Cannabidiol as a Potential Treatment for Anxiety Disorders - PMC
3) Clinical and cognitive improvement following full-spectrum, high-cannabidiol treatment for anxiety: open-label data from a two-stage, phase 2 clinical trial
4) Combining cannabis and melatonin treatment with a rehabilitation program improved symptoms in a dog with compulsive disorder: A case report
5) Survey of Patients Employing Cannabigerol-Predominant Cannabis Preparations: Perceived Medical Effects, Adverse Events, and Withdrawal Symptoms
Ashwagandha:
1) Efficacy and safety of standardized Ashwagandha (Withania somnifera) root extract on reducing stress and anxiety in domestic dogs: A randomized controlled trial - ScienceDirect
2) Adaptogenic and Anxiolytic Effects of Ashwagandha Root Extract in Healthy Adults: A Double-blind, Randomized, Placebo-controlled Clinical Study
3) A prospective, randomized double-blind, placebo-controlled study of safety and efficacy of a high-concentration full-spectrum extract of ashwagandha root in reducing stress and anxiety in adults
Sesame Oil:
1) Inclusion of Medium-Chain Triglyceride in Lipid-Based Formulation of Cannabidiol Facilitates Micellar Solubilization In Vitro, but In Vivo Performance Remains Superior with Pure Sesame Oil Vehicle - PMC
2) Natural sesame oil is superior to pre-digested lipid formulations and purified triglycerides in promoting the intestinal lymphatic transport and systemic bioavailability of cannabidiol
The importance of 3rd party testing and available COAs:
1) Cannabinoid, Terpene, and Heavy Metal Analysis of 29 Over-the-Counter Commercial Veterinary Hemp Supplements - PMC
2) Leafreport Releases Findings From Pet CBD Report Showing 56% of Products Have Inaccurate Label Claims
